Are Mast Cell Activation Disorders (MCAD) being missed and heavily under-diagnosed in a large portion of patients with chronic illness? Could these easily misunderstood conditions be the cause of the rapid fluctuations in your health? Do you start out having a great day, only to have your energy levels plummet within hours or moments of leaving the house or even just eating or bathing? Your wildly fluctuating fatigue levels might be trying to tell you you’re a special kind of spoonie, referred to by some as a Mastie. MCADs are a common comorbid condition to Ehlers-Danlos Syndrome (EDS), Hypermobility Syndrome Disorders (HSD), Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Postural Orthostatic Tachycardia Syndrome (POTS), Neurally Mediated Hypotension (NMH), Fibromyalgia, Interstitial Cystitis and other spoonie conditions.

Masties are people with Mast Cell Activation Disorders (MCAD) including Mastocytosis and Mast Cell Activation Syndrome (MCAS). This group may also include people with histamine intolerance, who…